作者
Andrea Di Marco, Ignasi Anguera, Matthias Schmitt, Igor Klem, Tomas G Neilan, James A White, Marek Sramko, Pier Giorgio Masci, Andrea Barison, Peter Mckenna, Ify Mordi, Kristina H Haugaa, Francisco Leyva, Jorge Rodriguez Capitan, Hiroshi Satoh, Takeru Nabeta, Paolo Domenico Dallaglio, Niall G Campbell, Xavier Sabate, Angel Cequier
发表日期
2017/1
来源
JACC: Heart Failure
卷号
5
期号
1
页码范围
28-38
出版商
American College of Cardiology Foundation
简介
Objectives
The aim of this study was to evaluate the association between late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging and ventricular arrhythmias or sudden cardiac death (SCD) in patients with dilated cardiomyopathy (DCM).
Background
Risk stratification for SCD in DCM needs to be improved.
Methods
A systematic review and meta-analysis were conducted. A systematic search of PubMed and Ovid was performed, and observational studies that analyzed the arrhythmic endpoint (sustained ventricular arrhythmia, appropriate implantable cardioverter-defibrillator [ICD] therapy, or SCD) in patients with DCM, stratified by the presence or absence of LGE, were included.
Results
Twenty-nine studies were included, accounting for 2,948 patients. The studies covered a wide spectrum of DCM, with a mean left ventricular ejection fraction between 20% and 43%. LGE was significantly …
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A Di Marco, I Anguera, M Schmitt, I Klem, TG Neilan… - JACC: Heart Failure, 2017
