作者
Samir Sarikouch, Brigitte Peters, Matthias Gutberlet, Birte Leismann, Andrea Kelter-Kloepping, Hermann Koerperich, Titus Kuehne, Philipp Beerbaum
发表日期
2010/1
期刊
Circulation: Cardiovascular Imaging
卷号
3
期号
1
页码范围
65-76
出版商
Lippincott Williams & Wilkins
简介
Background— Cardiac MRI is important in the treatment of children with congenital heart disease, but sufficient normative data are lacking. For ventricular volumes and mass, we sought to deliver reference centiles and to investigate sex effects.
Methods and Results— We included 114 healthy children and adolescents, uniformly distributed spanning an age range of 4 to 20 years, as required by the Lambda-Mu-Sigma method to achieve a percentile distribution, thus avoiding arbitrary age categories. Subjects underwent axial volumetry (1.5-T scanner) using standardized 2D steady-state free-precession and flow protocols. Percentiles were computed for age 8 to 20 years (99 subjects) because breath-holds were more consistent in this group. When indexed for body surface area or height, the centile curves of ventricular volumetric parameters showed allometric increase until adolescence, when a plateau was …
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