作者
Debanjan Sarkar, Jui‐Chen Yang, Anirban Sen Gupta, Stephanie T Lopina
发表日期
2009/6
期刊
Journal of Biomedical Materials Research Part A: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials
卷号
90
期号
1
页码范围
263-271
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
The use of amino acid based polymers for biomaterial applications enhance biocompatibility and ensure biodegradability. Two polyurethanes based on L‐tyrosine based diphenolic dipeptide, desaminotyrosyl tyrosine hexyl ester as chain extender are synthesized with polyethylene glycol (PEG) and polycaprolactone diol (PCL) as soft segment and hexamethylene diisocyanate as diisocyanate. The chemical structure and molecular characteristics of the polymers were studied by 1H NMR, FTIR, and gel permeation chromatography. Results of DSC and TGA analysis were used for examining the thermal behavior of the polyurethanes. In addition, DSC results were used to analyze the morphology of the polymers, which shows characteristic microphase behavior of the polyurethanes. The tensile properties of the polyurethanes are primarily controlled by the soft segment and are higher in PCL based polymers. Contact …
学术搜索中的文章
D Sarkar, JC Yang, AS Gupta, ST Lopina - Journal of Biomedical Materials Research Part A: An …, 2009