作者
Evaldo Favi, Carmelo Puliatti, Samuele Iesari, Andrea Monaco, Mariano Ferraresso, Roberto Cacciola
发表日期
2018/10/1
期刊
Transplantation direct
卷号
4
期号
10
页码范围
e396
出版商
LWW
简介
Background
Standard-criteria donation after circulatory death (DCD) kidney transplants (KTx) have higher primary nonfunction, delayed graft function (DGF), and rejection rates than age-matched donation after brain death (DBD) but similar graft survival. Data on expanded-criteria DCD are conflicting and many centers remain concerned regarding their use.
Methods
In this single-center observational study with 5-year follow-up, we analyzed data from 112 primary DCD Maastricht category-III single KTx receiving similar organ preservation and maintenance immunosuppression. Patients were sorted as young DCD (donor< 60 years, 72 recipients) or old DCD (donor≥ 60 years, 40 recipients). Old DCD outcomes were compared with young DCD and to a DBD control group (old DBD, donor≥ 60 years, 40 recipients).
Results
After 5 years, old DCD showed lower patient survival (66% vs 85%; P= 0.014), death-censored …
引用总数
20192020202120222023202425781