作者
Syeda Fatima Naqvi, Dhairya A Lakhani, Amir Humza Sohail, James Maurer, Sarah Sofka, Arif Sarwari, Yousaf B Hadi
发表日期
2021/8/1
期刊
BMJ Open Respiratory Research
卷号
8
期号
1
页码范围
e000969
出版商
Archives of Disease in childhood
简介
Introduction
Outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with pre-existing idiopathic pulmonary fibrosis (IPF) remain understudied, and it is unknown if IPF is an independent predictor of worse disease course. Herein, we report the clinical outcomes in a large cohort of 251 patients with COVID-19 in the setting of known IPF. Outcomes were compared with a propensity matched cohort of patients with COVID-19 without IPF.
Methods
Analysis of a federated multicentre research network TriNetX was performed including patients more than 16 years of age diagnosed with SARS-CoV-2 infection. Outcomes in patients diagnosed as positive for SARS-CoV-2 infection with concurrent IPF were compared with a propensity matched cohort of patients without IPF.
Results
A total of 311 060 patients with SARS-CoV-2 infection on the research network were identified, 251 …
学术搜索中的文章
SF Naqvi, DA Lakhani, AH Sohail, J Maurer, S Sofka… - BMJ Open Respiratory Research, 2021