作者
Celina Ang, David Hauerstock, Marie‐Christine Guiot, Goulnar Kasymjanova, David Roberge, Petr Kavan, Thierry Muanza
发表日期
2008/11
期刊
Pediatric blood & cancer
卷号
51
期号
5
页码范围
603-607
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Background
Adult medulloblastoma is a rare disease for which there is no internationally accepted standard of care. Treatment regimens have typically been modeled after pediatric protocols. We sought to review the presentation, management, and outcome of patients with adult medulloblastoma treated at the McGill University teaching hospitals over the past 18 years.
Methods
Medical records were reviewed to gather demographic and clinical data including presenting symptoms, tumor characteristics, management, survival, and treatment toxicity.
Results
Twenty‐five patients were identified. Eleven patients were female and 14 were male. The median age at diagnosis was 30 (range 17–48). Our 5‐ and 10‐year overall survival (OS) rates were 78% and 30%, respectively. Median OS was 108 months and median progression‐free survival time was 63 months. Age, sex, risk, stage, extent of resection …
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C Ang, D Hauerstock, MC Guiot, G Kasymjanova… - Pediatric blood & cancer, 2008