作者
Stephanie M Wong, Mark Basik, Livia Florianova, Richard Margolese, Sinziana Dumitra, Thierry Muanza, Annie Carbonneau, Cristiano Ferrario, Jean Francois Boileau
发表日期
2021/5
期刊
Annals of Surgical Oncology
卷号
28
页码范围
2621-2629
出版商
Springer International Publishing
简介
Background
The oncologic safety of sentinel lymph node biopsy (SLNB) alone for clinically node-positive (cN1–2) patients who convert to pathologic node-negativity (ypN0) after neoadjuvant chemotherapy (NAC) is not well established.
Methods
This study retrospectively identified 244 consecutive patients with a diagnosis of cT1–3cN0–2 breast cancer who underwent NAC followed by SLNB at the authors’ institution between 2013 and 2018. The patients were categorized as clinically node-negative (cN0) or cN1–2 before the onset of NAC, and the Kaplan–Meier method was used to compare locoregional and distant recurrence rates after SLNB alone for ypN0 patients.
Results
Among 244 patients who underwent NAC followed by surgery with SLNB for axillary staging, 112 (45.9%) were cN0 at presentation, whereas …
学术搜索中的文章
SM Wong, M Basik, L Florianova, R Margolese… - Annals of Surgical Oncology, 2021