作者
Ronen Ben-Ami, Jesús Rodríguez-Baño, Hande Arslan, Johann DD Pitout, Claudine Quentin, Esther S Calbo, Özlem K Azap, Corinne Arpin, Alvaro Pascual, David M Livermore, Javier Garau, Yehuda Carmeli
发表日期
2009/9/1
期刊
Clinical Infectious Diseases
卷号
49
期号
5
页码范围
682-690
出版商
The University of Chicago Press
简介
Background . Infections caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are increasing in frequency and are associated with high mortality rates. Circulation of CTX-M-type ESBLs in the community is of particular concern, because it may confound standard infection-control measures.
Methods . We analyzed the results of epidemiologic studies of infection caused by ESBL-producing Enterobacteriaceae in nonhospitalized patients from 6 centers in Europe, Asia, and North America. Risk factors for infection with an ESBL-producing organism were identified by univariate and multivariate analyses.
Results . A total of 983 patient-specific isolates were reviewed (890 [90.5%] of which were Escherichia coli, 68 [6.9%] of which were Klebsiella species, and 25 [2.5%] of which were Proteus mirabilis ); 339 [34.5%] of the …
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