作者
Jesús Rodríguez-Baño, Lorena López-Cerero, Maria D Navarro, Paula Díaz de Alba, Alvaro Pascual
发表日期
2008/11/1
期刊
Journal of antimicrobial chemotherapy
卷号
62
期号
5
页码范围
1142-1149
出版商
Oxford University Press
简介
Objectives
The aim of this study was to investigate the epidemiology of faecal carriage of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in the community.
Patients and methods
Faecal carriage with ESBL-producing E. coli was studied in 53 outpatients with urinary tract infection (UTI) due to these organisms, 73 household members, 32 non-household relatives and 54 unrelated patients. Clonal relatedness of the isolates was investigated using repetitive extragenic palindromic-PCR and PFGE, and ESBLs were characterized by PCR and sequencing. Multivariate analysis was performed to investigate risk factors for faecal carriage.
Results
The prevalence of faecal carriage was 67.9% in patients with UTI, 27.4% in household members, 15.6% in non-household relatives and 7.4% in unrelated patients. Being a relative of a patient with UTI …
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