作者
Michele Bartoletti, Renato Pascale, Monica Cricca, Matteo Rinaldi, Angelo Maccaro, Linda Bussini, Giacomo Fornaro, Tommaso Tonetti, Giacinto Pizzilli, Eugenia Francalanci, Lorenzo Giuntoli, Arianna Rubin, Alessandra Moroni, Simone Ambretti, Filippo Trapani, Oana Vatamanu, Vito Marco Ranieri, Andrea Castelli, Massimo Baiocchi, Russell Lewis, Maddalena Giannella, Pierluigi Viale
发表日期
2021/12/1
期刊
Clinical Infectious Diseases
卷号
73
期号
11
页码范围
e3606-e3614
出版商
Oxford University Press
简介
Background
We evaluated the incidence of invasive pulmonary aspergillosis among intubated patients with critical COVID-19 and evaluated different case definitions of invasive aspergillosis.
Methods
Prospective, multicenter study in adult patients with microbiologically confirmed COVID-19 receiving mechanical ventilation. All included participants underwent a screening protocol for invasive pulmonary aspergillosis with bronchoalveolar lavage galactomannan and cultures performed on admission at 7 days and in case of clinical deterioration. Cases were classified as coronavirus-associated pulmonary aspergillosis (CAPA) according to previous consensus definitions. The new definition was compared with putative invasive pulmonary aspergillosis (PIPA).
Results
108 patients were enrolled. Probable CAPA was diagnosed in 30 (27.7%) patients after a …
学术搜索中的文章
M Bartoletti, R Pascale, M Cricca, M Rinaldi, A Maccaro… - Clinical Infectious Diseases, 2021
M Bartoletti, R Pascale, M Cricca, M Rinaldi, A Maccaro… - … of invasive pulmonary aspergillosis among intubated …, 28
M Bartoletti, R Pascale, M Cricca, M Rinaldi, A Maccaro… - Clinical Infectious Diseases, 2020