作者
Teboho Amelia Tiiti, Tebogo Loraine Mashishi, Varsetile Varster Nkwinika, Ina Benoy, Selokela Gloria Selabe, Johannes Bogers, Ramokone Lisbeth Lebelo
发表日期
2021/12
期刊
Virology Journal
卷号
18
页码范围
1-9
出版商
BioMed Central
简介
Background
In 2017, the South African National Department of Health (NDoH) Cervical Cancer Prevention and Control Policy was revised. Human papillomavirus (HPV) testing on self-collected samples may offer improved screening uptake. The objectives of the study were to compare the positivity of high-risk (hr)-HPV deoxyribonucleic acid (DNA) and hrHPV viral messenger ribonucleic acid (mRNA) between healthcare worker-collected cervical and self-collected vaginal samples and investigate the accuracy of the applicator-tampon-based self-collected samples in detecting hrHPV DNA and hrHPV mRNA.
Methods
A total of 527 women aged 18 years and older and seeking gynecology services at a tertiary hospital in Pretoria, South Africa, were enrolled. Vaginal samples were self-collected using SelfCerv applicator tampon, followed by cervical …
学术搜索中的文章
TA Tiiti, TL Mashishi, VV Nkwinika, I Benoy, SG Selabe… - Virology Journal, 2021