作者
Amir H Zamanipoor Najafabadi, Pim B van der Meer, Florien W Boele, Martin JB Taphoorn, Martin Klein, Saskia M Peerdeman, Wouter R van Furth, Linda Dirven, Dutch Meningioma Consortium Florien W. Boele Linda Dirven Wouter R. van Furth Martin Klein Johan Koekkoek Frank Lagerwaard Pim B. van der Meer Saskia M. Peerdeman Martin JB Taphoorn Amir H. Zamanipoor Najafabadi Wouter A. Moojen Jaap C. Reijneveld
发表日期
2021/1
期刊
Journal of Neuro-oncology
卷号
151
页码范围
201-210
出版商
Springer US
简介
Introduction
Meningioma is a heterogeneous disease and patients may suffer from long-term tumor- and treatment-related sequelae. To help identify patients at risk for these late effects, we first assessed variables associated with impaired long-term health-related quality of life (HRQoL) and impaired neurocognitive function on group level (i.e. determinants). Next, prediction models were developed to predict the risk for long-term neurocognitive or HRQoL impairment on individual patient-level.
Methods
Secondary data analysis of a cross-sectional multicenter study with intracranial WHO grade I/II meningioma patients, in which HRQoL (Short-Form 36) and neurocognitive functioning (standardized test battery) were assessed. Multivariable regression models were used to assess determinants for these outcomes corrected for confounders, and to build …
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AH Zamanipoor Najafabadi, PB van der Meer… - Journal of Neuro-oncology, 2021