作者
Zeynep Atay, Ediz Yesilkaya, Senay Savas Erdeve, Serap Turan, Leyla Akin, Erdal Eren, Esra Doger, Zehra Aycan, Zehra Yavas Abali, Aysşehan Akinci, Zeynep Siklar, Samim Ozen, Cengiz Kara, Meltem Tayfun, Erkan Sari, Filiz Tutunculer, Gulcan Seymen Karabulut, Gulay Karaguzel, Semra Cetinkaya, Halil Saglam, Aysun Bideci, Selim Kurtoglu, Tulay Guran, Abdullah Bereket
发表日期
2016/5/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
101
期号
5
页码范围
1980-1988
出版商
Oxford University Press
简介
Aim
The causes of gonadotropin-independent precocious puberty are diverse, and often have overlapping clinical and biochemical features. With the exception of congenital adrenal hyperplasia (CAH), disorders that cause gonadotropin-independent precocious puberty (GIPP) are uncommon. The literature is devoid of any large-scale studies on the etiologic distribution of GIPP. The aim of this study was to determine the frequency of each etiology in a cohort of patients with GIPP (excluding those with CAH), and to evaluate the clinical and laboratory features of these patients.
Materials and Methods
This multicenter, nationwide web-based study collected data on patients who presented with non-CAH GIPP in Turkey.
Results
Data were collected for 129 patients (102 girls and 27 boys) from 29 centers. Based on the data collected, the estimated prevalence of …
学术搜索中的文章
Z Atay, E Yesilkaya, SS Erdeve, S Turan, L Akin, E Eren… - The Journal of Clinical Endocrinology & Metabolism, 2016