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Cannabis plant has been used for several purposes since ancestral times. For example, for the manufacture of textiles, as a food, in rituals, as a recreational drug, but the most important use was as a remedy. The use of cannabis with medical purposes was reported in the worlds oldest pharmacopeia, the pen-tsao ching and the indications for the use of cannabis included rheumatic pain, intestinal constipation, and malaria, among other prescriptions. The plants’ psychoactive and medicinal effects were appreciated, hence, spread out from Asia to Europe at