作者
Riccardo Proietti, José Miguel Rivera‐Caravaca, Raquel López‐Gálvez, Stephanie L Harrison, Benjamin JR Buckley, Francisco Marin, Paula Underhill, Eduard Shantsila, Alena Shantsila, Rhys Davies, Deirdre A Lane, Gregory YH Lip
发表日期
2023/6
期刊
Clinical Cardiology
卷号
46
期号
6
页码范围
656-662
简介
Background
Atrial fibrillation (AF) associates with higher Alzheimer's disease (AD) and vascular dementia risks but the clinical implications have been scarcely investigated. We examined the association between AD or vascular dementia and adverse outcomes in AF patients.
Methods
Cohort study between January 2000 and 2017. AF patients were divided into two groups according to vascular dementia or AD, and balanced using propensity score matching (PSM). During 4‐years of follow‐up, incident intracranial hemorrhages (ICH), the composite of ischemic stroke/transient ischemic attack (TIA), hospitalizations, and all‐cause deaths, were recorded.
Results
Two thousand three hundred seventy‐seven AF patients with dementia (1225 with vascular dementia, and 1152 with AD) were identified. Following a PSM, 615 patients were included in each cohort (i.e., 1:1) and all variables were well‐matched. After …
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R Proietti, JM Rivera‐Caravaca, R López‐Gálvez… - Clinical Cardiology, 2023