作者
Safaet Alam, Mohammad A Rashid, Md Moklesur Rahman Sarker, Nazim Uddin Emon, Mohammad Arman, Isa Naina Mohamed, Mohammad Rashedul Haque
发表日期
2021/4/12
期刊
BMC Complementary Medicine and Therapies
卷号
21
期号
1
页码范围
119
出版商
BioMed Central
简介
Background
Colocasia gigantea, locally named as kochu is well-known due to its various healing power. This research is to investigate the antidiarrheal, antimicrobial and antioxidant possibilities of the methanol soluble extract of Colocasia gigantea.
Methods
The antidiarrheal investigation was performed by using in vivo castor oil-induced diarrheal method whereas in vitro antimicrobial and antioxidant investigation have been implemented by disc diffusion and DPPH scavenging method respectively. Moreover, in silico studies were followed by molecular docking analysis of several secondary metabolites that were appraised with Schrödinger-Maestro v11.1 and Biovia Discovery Studio.
Results
The induction of plant extract (200 and 400 mg/kg, b.w, p.o) has minimized the castor oil mediated diarrhea by 16.96% (p < …
学术搜索中的文章
S Alam, MA Rashid, MMR Sarker, NU Emon, M Arman… - BMC Complementary Medicine and Therapies, 2021