作者
Adam RM Herman, Christopher Cheung, Brenda Gerull, Christopher S Simpson, David H Birnie, George J Klein, Jean Champagne, Jeffrey S Healey, Karen Gibbs, Mario Talajic, Martin Gardner, Matthew T Bennett, Christian Steinberg, Mikyla Janzen, Michael H Gollob, Paul Angaran, Raymond Yee, Richard Leather, Santabhanu Chakrabarti, Shubhayan Sanatani, Vijay S Chauhan, Andrew D Krahn
发表日期
2016/1/1
期刊
Circulation: Arrhythmia and Electrophysiology
卷号
9
期号
1
页码范围
e003619
出版商
American Heart Association, Inc.
简介
Background
The Cardiac Arrest Survivors with Preserved Ejection Fraction Registry (CASPER) enrolls patients with apparently unexplained cardiac arrest and no evident cardiac disease to identify the pathogenesis of cardiac arrest through systematic clinical testing. Exercise testing, drug provocation, advanced cardiac imaging, and genetic testing may be useful when a cause is not apparent.
Methods and Results
The first 200 survivors of unexplained cardiac arrest from 14 centers across Canada were evaluated to determine the results of investigation and follow-up (age, 48.6±14.7 years, 41% female). Patients were free of evidence of coronary artery disease, left ventricular dysfunction, or evident repolarization syndromes. Advanced testing determined a diagnosis in 34% of patients at baseline, with a diagnosis emerging during follow-up in 7% of patients. Of those who were diagnosed, 28 (35%) had an underlying …
引用总数
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