作者
Fatima Amanat, Daniel Stadlbauer, Shirin Strohmeier, Thi HO Nguyen, Veronika Chromikova, Meagan McMahon, Kaijun Jiang, Guha Asthagiri Arunkumar, Denise Jurczyszak, Jose Polanco, Maria Bermudez-Gonzalez, Giulio Kleiner, Teresa Aydillo, Lisa Miorin, Daniel S Fierer, Luz Amarilis Lugo, Erna Milunka Kojic, Jonathan Stoever, Sean TH Liu, Charlotte Cunningham-Rundles, Philip L Felgner, Thomas Moran, Adolfo García-Sastre, Daniel Caplivski, Allen C Cheng, Katherine Kedzierska, Olli Vapalahti, Jussi M Hepojoki, Viviana Simon, Florian Krammer
发表日期
2020/7
期刊
Nature medicine
卷号
26
期号
7
页码范围
1033-1036
出版商
Nature Publishing Group US
简介
Here, we describe a serological enzyme-linked immunosorbent assay for the screening and identification of human SARS-CoV-2 seroconverters. This assay does not require the handling of infectious virus, can be adjusted to detect different antibody types in serum and plasma and is amenable to scaling. Serological assays are of critical importance to help define previous exposure to SARS-CoV-2 in populations, identify highly reactive human donors for convalescent plasma therapy and investigate correlates of protection.
学术搜索中的文章
F Amanat, D Stadlbauer, S Strohmeier, THO Nguyen… - Nature medicine, 2020