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The effects of low doses of d-amphetamine (0.25–0.5 mg/kg, IP) on taste reactions elicited by quinine solutions in a 5–10-min taste reactivity test were assessed in a series of three experiments. Amphetamine consistently suppressed aversive reactions elicited by quinine solutions. The results suggest that amphetamine, like morphine, attenuates the aversiveness of the taste of quinine solution.