作者
Osama M Ahmed, Mahmoud A Mohamed, Rasha R Ahmed, Sayed A Ahmed
发表日期
2009/9/1
期刊
European journal of medicinal chemistry
卷号
44
期号
9
页码范围
3519-3523
出版商
Elsevier Masson
简介
Cyclocondensation of cyanoacetamide, cyanothioacetamide and 3-aminopyrazols with sodium salt of 3-hydroxy-1-(2-naphthyl)prop-2-en-1-one gives pyridin-2-one, pyridin-2(1H)-thione, and pyrazolo[1,5-a]pyrimidine derivatives. These derivatives showed potent anti-tumor cytotoxic activity in vitro using different human cancer cell lines.
学术搜索中的文章
OM Ahmed, MA Mohamed, RR Ahmed, SA Ahmed - European journal of medicinal chemistry, 2009