作者
Marco Piastra, Daniele De Luca, Roberta Costa, Alessandro Pizza, Renata De Sanctis, Laura Marzano, Daniele Biasucci, Federico Visconti, Giorgio Conti
发表日期
2014/4/1
期刊
Journal of critical care
卷号
29
期号
2
页码范围
312. e1-312. e5
出版商
WB Saunders
简介
Objective
Neurally adjusted ventilatory assist (NAVA) is a new ventilator modality with an innovative synchronization technique. Our aim is to verify if NAVA is feasible and safe in terms of physiological and clinical variables in infants recovering from severe acute respiratory distress syndrome (ARDS).
Design
This is a pilot nested study to help future trial design.
Setting
The study was performed in third-level academic pediatric intensive care units.
Patients
Infants affected by severe ARDS requiring high-frequency ventilation and weaned with NAVA during 2010 were included. Controls (2:1 ratio) were ARDS infants weaned with pressure support ventilation (PSV) during 2008-2009 matched for age, gas exchange impairment, and weight.
Main outcome measures
The main outcome measures were the physiological and ventilator parameters and the duration of ventilator support in PSV or NAVA.
Results
Ten infants treated …
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M Piastra, D De Luca, R Costa, A Pizza, R De Sanctis… - Journal of critical care, 2014