作者
Raquel Nichele de Chaves, Adam Baxter-Jones, Daniel Santos, Thayse Natacha Gomes, Fernanda Karina dos Santos, Michele Caroline de Souza, Vincent Paul Diego, José Maia
发表日期
2014/3/1
期刊
Annals of human biology
卷号
41
期号
2
页码范围
159-167
出版商
Taylor & Francis
简介
Aim: The purposes of this study were: (i) to identify familial resemblances in body fat, blood pressure (BP) and total physical activity (TPA); (ii) to estimate the magnitude of their genetic and environmental influences; and (iii) to investigate shared familial aggregation among these phenotypes.
Subjects and methods: The sample comprised 260 nuclear families from Portugal. Body fat was assessed by bioelectrical impedance. BP was measured by an oscillometric device. TPA was estimated by the Baecke questionnaire. Familial correlation analyses were performed using Generalized Estimating Equations. Quantitative genetic modelling was used to estimate maximal heritability, genetic and environmental correlations.
Results: Familial intra-trait correlations ranged from 0.15–0.38. Genetic and common environmental factors explained from 30%--44% of fat mass depots and BP and 24% of TPA. Genetic correlations …
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RN de Chaves, A Baxter-Jones, D Santos, TN Gomes… - Annals of human biology, 2014