作者
Colm P Travers, Nellie I Hansen, Abhik Das, Matthew A Rysavy, Edward F Bell, Namasivayam Ambalavanan, Myriam Peralta‐Carcelen, Alan T Tita, Krisa P Van Meurs, Waldemar A Carlo, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, Richard A Polin, Michael S Caplan, Abbott R Laptook, Martin Keszler, Angelita M Hensman, Andrea M Knoll, Emilee Little, Elisa Vieira, Kristin M Basso, Jennifer A Keller, Lucille St Pierre, Michele C Walsh, Anna Maria Hibbs, Avroy A Fanaroff, Nancy S Newman, Allison H Payne, William E Truog, Eugenia K Pallotto, Howard W Kilbride, Cheri Gauldin, Anne Holmes, Kathy Johnson, Allison Knutson, Prabhu S Parimi, Lisa Gaetano, Stephanie L Merhar, Brenda B Poindexter, Kurt Schibler, Edward F Donovan, Cathy Grisby, Barbara Alexander, Kate Bridges, Estelle E Fischer, Holly L Mincey, Jody Hessling, Lenora Jackson, Kristin Kirker, Greg Muthig, Stacey Tepe, C Michael Cotten, Ronald N Goldberg, Joanne Finkle, Kathy J Auten, Kimberley A Fisher, Matthew M Laughon, Carl L Bose, Janice Bernhardt, Gennie Bose, Cindy Clark, Stephen D Kicklighter, Ginger Rhodes‐Ryan, Donna White, Ravi M Patel, David P Carlton, Barbara J Stoll, Ellen C Hale, Yvonne Loggins, Diane I Bottcher, Colleen Mackie, Andrew A Bremer, Rosemary D Higgins, Stephanie Wilson Archer, Gregory M Sokol, Dianne E Herron, Jeff Joyce, Lucy Miller, Leslie Dawn Wilson, Jon E Tyson, Amir M Khan, Kathleen A Kennedy, Elizabeth Eason, Emily K Stephens, Georgia E McDavid, Julie Arldt‐McAlister, Katrina Burson, Carmen Garcia, Donna Hall, Beverly Foley Harris, Anna E Lis, Karen Martin, Sara C Martin, Shawna Rodgers, Maegan C Simmons, Patti L Pierce Tate, Pablo J Sanchez, Leif D Nelin, Sudarshan R Jadcherla, Patricia Luzader, Hallie Baugher, Erna Clark, Christine A Fortney, Julie Gutentag, Courtney Park, Julie C Shadd, Melanie Stein, Jennifer L Grothause, Jacqueline McCool, Nehal A Parikh, Lina Yosseff‐Salameh, Marie G Gantz, Carla M Bann, Dennis Wallace, Margaret M Crawford, Jenna Gabrio, David Leblond, Jeanette O’Donnell Auman, Carolyn M Petrie Huitema, Kristin M Zaterka‐Baxter, Valerie Y Chock, David K Stevenson, M Bethany Ball, Marian M Adams, Magdy Ismail, Andrew W Palmquist, Melinda S Proud, Elizabeth N Reichert, R Jordan Williams, Ivan D Frantz, John M Fiascone, Brenda L MacKinnon, Anne Furey, Ellen Nylen, Monica V Collins, Shirley S Cosby, Tara McNair, Meredith Estes, Kelli Hagood, Uday Devaskar, Meena Garg, Teresa Chanlaw, Rachel Geller, Neil N Finer, David Kaegi, Maynard R Rasmussen, Kathy Arnell, Clarence Demetrio, Wade Rich, Tarah T Colaizy, Michelle L Baack
发表日期
2022/11
期刊
BJOG: An International Journal of Obstetrics & Gynaecology
卷号
129
期号
12
页码范围
2039-2051
简介
Objective
To test the hypothesis that potential missed opportunities for antenatal corticosteroids increase as gestational age decreases and are associated with adverse outcomes.
Design
Observational cohort study.
Setting
Twenty‐four US centers in the Neonatal Research Network.
Population
Actively treated infants at 22–25 weeks of gestation and with birthweight 401–1000 g, without major birth defects, born 2006–18.
Methods
Potential missed opportunity was defined as no antenatal corticosteroids but did have prenatal antibiotics, and/or magnesium sulphate, and/or prolonged rupture of membranes. Poisson regression models adjusted for baseline characteristics.
Main outcome measures
Antenatal corticosteroid exposure, mortality and severe intracranial haemorrhage or periventricular leucomalacia.
Results
A total of 6966 (87.5%) infants were exposed to antenatal corticosteroids, 454 (5.7%) had …
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