作者
Kit Mun Chow, Wei Zheng So, Han Jie Lee, Alvin Lee, Dominic Wei Ting Yap, Yemisi Takwoingi, Kae Jack Tay, Jeffrey Tuan, Sue Ping Thang, Winnie Lam, John Yuen, Nathan Lawrentschuk, Michael S Hofman, Declan G Murphy, Kenneth Chen
发表日期
2023/7/1
来源
European urology
卷号
84
期号
1
页码范围
36-48
出版商
Elsevier
简介
Context
Whether prostate-specific membrane antigen positron emission tomography (PSMA-PET) should replace conventional imaging modalities (CIM) for initial staging of intermediate-high risk prostate cancer (PCa) requires definitive evidence on their relative diagnostic abilities.
Objective
To perform head-to-head comparisons of PSMA-PET and CIM including multiparametric magnetic resonance imaging (mpMRI), computed tomography (CT) and bone scan (BS) for upfront staging of tumour, nodal, and bone metastasis.
Evidence acquisition
A search of the PubMed, EMBASE, CENTRAL, and Scopus databases was conducted from inception to December 2021. Only studies in which patients underwent both PSMA-PET and CIM and imaging was referenced against histopathology or composite reference standards were included. Quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 …
引用总数