作者
Jason J Chang, Ehsan Dowlati, Matthew Triano, Enite Kalegha, Rashi Krishnan, Brittany M Kasturiarachi, Leila Gachechiladze, Abhi Pandhi, Marios Themistocleous, Aristeidis H Katsanos, Daniel R Felbaum, Jeffrey C Mai, Rocco A Armonda, Edward F Aulisi, Lucas Elijovich, Adam S Arthur, Georgios Tsivgoulis, Nitin Goyal
发表日期
2021/9/1
期刊
Journal of Stroke and Cerebrovascular Diseases
卷号
30
期号
9
页码范围
105936
出版商
WB Saunders
简介
Purpose
We sought to evaluate the relationship between admission neutrophil-to-lymphocyte ratio (NLR) and functional outcome in aneurysmal subarachnoid hemorrhage (aSAH) patients.
Material and methods
Consecutive patients with aSAH were treated at two tertiary stroke centers during a five-year period. Functional outcome was defined as discharge modified Rankin score dichotomized at scores 0-2 (good) vs. 3-6 (poor).
Results
474 aSAH patients were evaluated with a mean NLR 8.6 (SD 8.3). In multivariable logistic regression analysis, poor functional outcome was independently associated with higher NLR, older age, poorer clinical status on admission, prehospital statin use, and vasospasm. Increasing NLR analyzed as a continuous variable was independently associated with higher odds of poor functional outcome (OR 1.03, 95%CI 1.00-1.07, p=0.05) after adjustment for potential confounders. When …
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JJ Chang, E Dowlati, M Triano, E Kalegha, R Krishnan… - Journal of Stroke and Cerebrovascular Diseases, 2021