作者
Stevie Hendriks, Kirsten Peetoom, Christian Bakker, Wiesje M Van Der Flier, Janne M Papma, Raymond Koopmans, Frans RJ Verhey, Marjolein De Vugt, Sebastian Köhler, Adrienne Withall, Juliette L Parlevliet, Özgül Uysal-Bozkir, Roger C Gibson, Susanne M Neita, Thomas Rune Nielsen, Lise C Salem, Jenny Nyberg, Marcos Antonio Lopes, Jacqueline C Dominguez, Ma Fe De Guzman, Alexander Egeberg, Kylie Radford, Tony Broe, Mythily Subramaniam, Edimansyah Abdin, Amalia C Bruni, Raffaele Di Lorenzo, Kate Smith, Leon Flicker, Merel O Mol, Maria Basta, Doris Yu, Golden Masika, Maria S Petersen, Luis Ruano, Young-Onset Dementia Epidemiology Study Group
发表日期
2021/9/1
来源
JAMA neurology
卷号
78
期号
9
页码范围
1080-1090
出版商
American Medical Association
简介
Importance
Reliable prevalence estimates are lacking for young-onset dementia (YOD), in which symptoms of dementia start before the age of 65 years. Such estimates are needed for policy makers to organize appropriate health care.
Objective
To determine the global prevalence of YOD.
Data Sources
The PubMed, Embase, CINAHL, and PsycInfo databases were systematically searched for population-based studies on the prevalence of YOD published between January 1, 1990, and March 31, 2020.
Study Selection
Studies containing data on the prevalence of dementia in individuals younger than 65 years were screened by 2 researchers for inclusion in a systematic review and meta-analysis.
Data Extraction and Synthesis
Prevalence estimates on 5-year age bands, from 30 to 34 years to 60 to 64 years, were extracted. Random-effects meta-analyses were conducted to pool prevalence estimates. Results were age …
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S Hendriks, K Peetoom, C Bakker, WM Van Der Flier… - JAMA neurology, 2021