作者
Bharat Rekhi, Bharti Patil, Kedar K Deodhar, Amita Maheshwari, Rajendra A Kerkar, Sudeep Gupta, Hemant B Tongaonkar, Shyam Kishore Shrivastava
发表日期
2013/2/1
期刊
Annals of diagnostic pathology
卷号
17
期号
1
页码范围
1-9
出版商
WB Saunders
简介
Neuroendocrine carcinomas of the cervix are uncommon, characterized by a histomorphological spectrum and, mostly, an aggressive clinical course. There are only few substantial studies on such cases documented from our country, where cervical cancer is the second most common cancer affecting women. Herein, we present a spectrum of 50 cervical neuroendocrine carcinomas, including histopathologic features, terminology, immunohistochemical (IHC) profile, and clinical outcomes, wherever available. Fifty tumors occurred in women, with their age ranging from 23 to 69 years (mean, 48.6 years; median, 46.5 years). Stagewise, among 25 cases, most cases (6, or 24%) presented with stage IB. Average tumor size was 4.7 cm. On histopathologic review, 26 tumors (52%) were classified as small cell carcinoma (SMCA); 14 (28%), as large cell neuroendocrine carcinomas (LCNECs); 4 (8%), as SMCA+LCNECs …
引用总数
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