作者
Anne Berberich, Stephanos Finitsis, Davide Strambo, Patrik Michel, Christian Herweh, Lukas Meyer, Uta Hanning, Daniel Strbian, Mohamad Abdalkader, Raul G Nogueira, Volker Puetz, Daniel PO Kaiser, Marta Olive‐Gadea, Marc Ribo, Isabel Fragata, João Pedro Marto, Michele Romoli, Peter A Ringleb, Thanh N Nguyen, Simon Nagel
发表日期
2022/5
来源
European Journal of Neurology
简介
Background and purpose
Endovascular therapy (EVT) is increasingly reported for treatment of isolated posterior cerebral artery (PCA) occlusions although its clinical benefit remains uncertain. This study‐level meta‐analysis investigated the functional outcomes and safety of EVT and best medical management (BMM) compared to BMM alone for treatment of PCA occlusion stroke.
Methods
We conducted a literature search in PubMed, Web of Science and Embase for studies in patients with isolated PCA occlusion stroke treated with EVT + BMM or BMM including intravenous thrombolysis. There were no randomized trials and all studies were retrospective. The primary outcome was modified Rankin Scale score of 0–2 at 3 months, while safety outcomes included mortality rate and incidence of symptomatic intracranial hemorrhage (sICH).
Results
Twelve studies with a total of 679 patients were included in the …
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A Berberich, S Finitsis, D Strambo, P Michel, C Herweh… - European Journal of Neurology, 2022