作者
Jose S Aguilar-Gallardo, Francisco Jose Romeo, Kirtipal Bhatia, Ashish Correa, Jeffrey Ian Mechanick, Johanna Paola Contreras
发表日期
2022/8/15
期刊
The American journal of cardiology
卷号
177
页码范围
53-60
出版商
Excerpta Medica
简介
Obesity is associated with reduced mortality in some patients hospitalized for heart failure (HF). In this analysis, we determine if this nonlinear relation, referred to as the obesity paradox, extends to secondary outcomes in patients diagnosed with severe obesity. This is a retrospective cohort study using the 2017 and 2018 National Inpatient Sample that includes adults hospitalized for HF. Patients with diagnosis codes specifying severe obesity, nonsevere obesity, or without obesity are compared. The primary outcome is mortality. Secondary outcomes include the length of stay (LOS), total charges, and cardiogenic shock (CS). Multivariate regression is used to adjust for demographics and co-morbidities. A total of 2,439,845 hospitalizations are included. A decreased mortality is found in nonsevere obesity (odds ratio 0.74, 95% confidence interval 0.69 to 0.80, p = 0.000), affirming the obesity paradox. However, this …
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JS Aguilar-Gallardo, FJ Romeo, K Bhatia, A Correa… - The American journal of cardiology, 2022