作者
Young-Pil Kim, Weston L Daniel, Zuyong Xia, Hexin Xie, Chad A Mirkin, Jianghong Rao
发表日期
2010
期刊
Chemical communications
卷号
46
期号
1
页码范围
76-78
出版商
Royal Society of Chemistry
简介
This communication reports the use of click chemistry to site-specifically conjugate bioluminescent Renilla luciferase proteins to gold nanoparticles (Au NPs) for sensing protease activity. The bioluminescent emission from luciferase was efficiently quenched by Au NPs, but significantly recovered after the proteolytic cleavage.
学术搜索中的文章
Bioluminescent nanosensors for protease detection based upon gold nanoparticle–luciferase conjugates
YP Kim, WL Daniel, Z Xia, H Xie, CA Mirkin, J Rao - Chemical communications, 2010