作者
Huan Guo, Bryan A Bassig, Qing Lan, Yong Zhu, Yawei Zhang, Theodore R Holford, Brian Leaderer, Peter Boyle, Qin Qin, Cairong Zhu, Ni Li, Nathaniel Rothman, Tongzhang Zheng
发表日期
2014/10
期刊
Cancer Causes & Control
卷号
25
页码范围
1261-1270
出版商
Springer International Publishing
简介
Purpose
Genetic polymorphisms in DNA repair genes and hair dye use may both have a role in the development of non-Hodgkin lymphoma (NHL). We aimed to examine the interaction between variants in DNA repair genes and hair dye use with risk of NHL in a population-based case–control study of Connecticut women.
Methods
We examined 24 single nucleotide polymorphisms in 16 DNA repair genes among 518 NHL cases and 597 controls and evaluated the associations between hair dye use and risk of overall NHL and common NHL subtypes, stratified by genotype, using unconditional logistic regression.
Results
Women who used hair dye before 1980 had a significantly increased risk of NHL, particularly for the follicular lymphoma (FL) subtype, but not for diffuse large B-cell lymphoma. The following genotypes …
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