作者
Aman Saini, Tae Hyun Oh, Dory Anthony Ghanem, Megan Castro, Matthew Butler, Chun Chiang Sin Fai Lam, Sotiris Posporelis, Glyn Lewis, Anthony S David, Jonathan P Rogers
发表日期
2022/10/3
期刊
Aging & Mental Health
卷号
26
期号
10
页码范围
2054-2061
出版商
Routledge
简介
Objectives
We aimed to find the association of inflammation and respiratory failure with delirium in COVID-19 patients. We compare the inflammatory and arterial blood gas markers between patients with COVID-19 delirium and delirium in other medical disorders.
Methods
This cross-sectional study used the CHART-DEL, a validated research tool, to screen patients for delirium retrospectively from clinical notes. Inflammatory markers C-reactive protein (CRP) and white cell count (WBC), and the partial pressures of oxygen (PO2) and carbon dioxide (PCO2) were compared between patients with COVID-19 delirium and delirium in other medical disorders.
Results
In bivariate analysis, CRP (mg/L) was significantly higher in the COVID-19 group, (81.7 ± 80.0 vs. 58.8 ± 87.7, p = 0.04), and WBC (109/L) was significantly lower (7.44 ± 3.42 vs. 9.71 ± 5.45, p = 0.04). The geometric mean of CRP in the COVID-19 …
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A Saini, TH Oh, DA Ghanem, M Castro, M Butler… - Aging & Mental Health, 2022