作者
Øyvind Ellingsen, Martin Halle, Viviane Conraads, Asbjørn Støylen, Håvard Dalen, Charles Delagardelle, Alf-Inge Larsen, Torstein Hole, Alessandro Mezzani, Emeline M Van Craenenbroeck, Vibeke Videm, Paul Beckers, Jeffrey W Christle, Ephraim Winzer, Norman Mangner, Felix Woitek, Robert Höllriegel, Axel Pressler, Tea Monk-Hansen, Martin Snoer, Patrick Feiereisen, Torstein Valborgland, John Kjekshus, Rainer Hambrecht, Stephan Gielen, Trine Karlsen, Eva Prescott, Axel Linke
发表日期
2017/2/28
期刊
Circulation
卷号
135
期号
9
页码范围
839-849
出版商
Lippincott Williams & Wilkins
简介
Background
Small studies have suggested that high-intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in patients with heart failure with reduced ejection fraction. The present multicenter trial compared 12 weeks of supervised interventions of HIIT, MCT, or a recommendation of regular exercise (RRE).
Methods
Two hundred sixty-one patients with left ventricular ejection fraction ≤35% and New York Heart Association class II to III were randomly assigned to HIIT at 90% to 95% of maximal heart rate, MCT at 60% to 70% of maximal heart rate, or RRE. Thereafter, patients were encouraged to continue exercising on their own. Clinical assessments were performed at baseline, after the intervention, and at follow-up after 52 weeks. Primary end point was a between-group comparison of change in left ventricular end-diastolic …
学术搜索中的文章
Ø Ellingsen, M Halle, V Conraads, A Støylen, H Dalen… - Circulation, 2017