作者
Jenny Lin, Ravi N Sharaf, Rachel Saganty, Danyal Ahsan, Julia Feit, Andrea Khoury, Hannah Bergeron, Eloise Chapman-Davis, Evelyn Cantillo, Kevin Holcomb, Stephanie V Blank, Ying Liu, Charlene Thomas, Paul J Christos, Drew N Wright, Steven Lipkin, Kenneth Offit, Melissa K Frey
发表日期
2021/8/1
来源
Gynecologic oncology
卷号
162
期号
2
页码范围
506-516
出版商
Academic Press
简介
Purpose
Several professional organizations recommend universal genetic assessment for people with ovarian cancer as identifying pathogenic variants can affect treatment, prognosis, and all-cause mortality for patients and relatives. We sought to evaluate the literature on genetic assessment for women with ovarian cancer and determine if any interventions or patient characteristics drive utilization of services.
Methods
We searched key electronic databases to identify trials that evaluated genetic assessment for people with ovarian cancer. Trials with the primary aim to evaluate utilization of genetic assessment with or without interventions were included. Eligible trials were subjected to meta-analysis and the moderating influence of health interventions on rates of genetic assessment were examined.
Results
A total of 35 studies were included (19 report on utilization of genetic services without an intervention, 7 with an …
学术搜索中的文章
J Lin, RN Sharaf, R Saganty, D Ahsan, J Feit, A Khoury… - Gynecologic oncology, 2021