作者
John J Hanna, Liyu B Geresu, Marlon I Diaz, Milan Ho, Julia A Casazza, Madison A Pickering, Heather D Lanier, Alexander P Radunsky, Lauren N Cooper, Sameh N Saleh, Roger J Bedimo, Zachary M Most, Trish M Perl, Christoph U Lehmann, Robert W Turer, Jeremy Y Chow, Richard J Medford
发表日期
2023/8
期刊
Open Forum Infectious Diseases
卷号
10
期号
8
页码范围
ofad400
出版商
Oxford University Press
简介
Background
Studies on COVID-19 in people with HIV (PWH) have had limitations. Further investigations on risk factors and outcomes of SARS-CoV-2 infection among PWH are needed.
Methods
This retrospective cohort study leveraged the national OPTUM COVID-19 data set to investigate factors associated with SARS-CoV-2 positivity among PWH and risk factors for severe outcomes, including hospitalization, intensive care unit stays, and death. A subset analysis was conducted to examine HIV-specific variables. Multiple variable logistic regression was used to adjust for covariates.
Results
Of 43 173 PWH included in this study, 6472 had a positive SARS-CoV-2 result based on a polymerase chain reaction test or antigen test. For PWH with SARS-CoV-2 positivity, higher odds were found for those who were younger (18–49 years), Hispanic White, African …
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JJ Hanna, LB Geresu, MI Diaz, M Ho, JA Casazza… - Open Forum Infectious Diseases, 2023