作者
Tobias Pischon, Petra H Lahmann, Heiner Boeing, Christine Friedenreich, Teresa Norat, Anne Tjønneland, Jytte Halkjaer, Kim Overvad, Françoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Gregory Guernec, Manuela M Bergmann, Jakob Linseisen, Nikolaus Becker, Antonia Trichopoulou, Dimitrios Trichopoulos, Sabina Sieri, Domenico Palli, Rosario Tumino, Paolo Vineis, Salvatore Panico, Petra HM Peeters, H Bas Bueno-de-Mesquita, Hendriek C Boshuizen, Bethany Van Guelpen, Richard Palmqvist, Göran Berglund, Carlos Alberto Gonzalez, Miren Dorronsoro, Aurelio Barricarte, Carmen Navarro, Carmen Martinez, J Ramón Quirós, Andrew Roddam, Naomi Allen, Sheila Bingham, Kay-Tee Khaw, Pietro Ferrari, Rudolf Kaaks, Nadia Slimani, Elio Riboli
发表日期
2006/7/5
期刊
Journal of the National Cancer Institute
卷号
98
期号
13
页码范围
920-931
出版商
Oxford University Press
简介
Background: Body weight and body mass index (BMI) are positively related to risk of colon cancer in men, whereas weak or no associations exist in women. This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women. Methods: We used multivariable adjusted Cox proportional hazards models to examine the association between anthropometric measures and risks of colon and rectal cancer among 368 277 men and women who were free of cancer at baseline from nine countries of the European Prospective Investigation Into Cancer and Nutrition. All statistical tests were two-sided. Results: During 6.1 years of follow-up, we identified 984 and 586 patients with colon and rectal cancer, respectively. Body weight and BMI were statistically significantly associated with colon cancer risk in …
引用总数
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T Pischon, PH Lahmann, H Boeing, C Friedenreich… - Journal of the National Cancer Institute, 2006
