作者
Chris C Patterson, Eva Gyürüs, Joachim Rosenbauer, Ondrej Cinek, Anna Neu, Edith Schober, Roger C Parslow, Geir Joner, Jannet Svensson, C Castell, Polly J Bingley, Eugene Schoenle, P Jarosz-Chobot, Brone Urbonaité, Ulrike Rothe, C Krzisnik, Constantin Ionescu-Tirgoviste, I Weets, M Kocova, Gordana Stipancic, Mira Samardzic, Carine E de Beaufort, A Green, GG Dahlquist, Gyula Soltesz
发表日期
2012/8
期刊
Diabetologia
卷号
55
页码范围
2142-2147
出版商
Springer-Verlag
简介
Aims/hypothesis
The aim of the study was to describe 20-year incidence trends for childhood type 1 diabetes in 23 EURODIAB centres and compare rates of increase in the first (1989–1998) and second (1999–2008) halves of the period.
Methods
All registers operate in geographically defined regions and are based on a clinical diagnosis. Completeness of registration is assessed by capture–recapture methodology. Twenty-three centres in 19 countries registered 49,969 new cases of type 1 diabetes in individuals diagnosed before their 15th birthday during the period studied.
Results
Ascertainment exceeded 90% in most registers. During the 20-year period, all but one register showed statistically significant changes in incidence, with rates universally increasing. When estimated separately for the first and second …
引用总数
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