作者
Christopher C Patterson, Valma Harjutsalo, Joachim Rosenbauer, Andreas Neu, Ondrej Cinek, Torild Skrivarhaug, Birgit Rami-Merhar, Gyula Soltesz, Jannet Svensson, Roger C Parslow, Conxa Castell, Eugen J Schoenle, Polly J Bingley, Gisela Dahlquist, Przemysława K Jarosz-Chobot, Dalė Marčiulionytė, Edna F Roche, Ulrike Rothe, Natasa Bratina, Constantin Ionescu-Tirgoviste, Ilse Weets, Mirjana Kocova, Valentino Cherubini, Natasa Rojnic Putarek, Carine E Debeaufort, Mira Samardzic, Anders Green
发表日期
2019/3
期刊
Diabetologia
卷号
62
页码范围
408-417
出版商
Springer Berlin Heidelberg
简介
Aims/hypothesis
Against a background of a near-universally increasing incidence of childhood type 1 diabetes, recent reports from some countries suggest a slowing in this increase. Occasional reports also describe cyclical variations in incidence, with periodicities of between 4 and 6 years.
Methods
Age/sex-standardised incidence rates for the 0- to 14-year-old age group are reported for 26 European centres (representing 22 countries) that have registered newly diagnosed individuals in geographically defined regions for up to 25 years during the period 1989–2013. Poisson regression was used to estimate rates of increase and test for cyclical patterns. Joinpoint regression software was used to fit segmented log-linear relationships to incidence trends.
Results
Significant increases in incidence were noted in all but two …
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