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The recent onset of the coronavirus pandemic (COVID-19) has raised concerns that people who smoke may be at a greater risk of harm from infection 1 given the impact of cigarettes on respiratory disease and immune function. 2 Similarly, there is concern that electronic cigarette (EC) use may increase harm from COVID-19, 1 though evidence is lacking. 3 While a systematic review concluded that cigarette smoking is likely associated with increased harm from COVID-19, 4 a meta-analysis did not. 5 However, as noted by Berlin et al., 6 the meta-analysis was limited by small sample sizes, resulting in large confidence intervals. 5 Berlin et al. describe findings from case series of smoking and COVID-19 as well as research from a prior coronavirus epidemic (MERS-CoV) that appear to support the association between smoking and adverse outcomes from COVID-19. 6 Regardless of the evidence on smoking and …