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Pacemakers, implantable cardiac defibrillators (ICDs), and cardiac resynchronization therapy (CRT) devices are lifesaving treatments for a number of cardiac conditions. Device-related infection is, however, one of the most serious complications of cardiac implantable electronic device (CIED) therapy. The recognition of gaps in knowledge, reports of new important randomized trials, observed divergences in managing device-related infections, 1 and the lack of international consensus documents specifically focusing on CIED infections provided a strong incentive for a 2019 State-of-the-art Consensus document on management of CIED infections. This consensus document is an international collaboration among seven professional societies/associations with a writing group consisting of cardiologists with varying subspecialties, infectious disease specialists, imaging specialist, and thoracic surgeon, from 11 countries in