作者
Liisa AM Galea, Karyn M Frick, Elizabeth Hampson, Farida Sohrabji, Elena Choleris
发表日期
2017/5/1
来源
Neuroscience & Biobehavioral Reviews
卷号
76
页码范围
363-379
出版商
Pergamon
简介
The National Institutes of Health (NIH) has required the inclusion of women in clinical studies since 1993, which has enhanced our understanding of how biological sex affects certain medical conditions and allowed the development of sex-specific treatment protocols. However, NIH’s policy did not previously apply to basic research, and the NIH recently introduced a new policy requiring all new grant applications to explicitly address sex as a biological variable. The policy itself is grounded in the results of numerous investigations in animals and humans illustrating the existence of sex differences in the brain and behavior, and the importance of sex hormones, particularly estrogens, in regulating physiology and behavior. Here, we review findings from our laboratories, and others, demonstrating how estrogens influence brain and behavior in adult females. Research from subjects throughout the adult lifespan on …
学术搜索中的文章
LAM Galea, KM Frick, E Hampson, F Sohrabji… - Neuroscience & Biobehavioral Reviews, 2017