作者
T Sonia Boender, Kim CE Sigaloff, Joshua Kayiwa, Victor Musiime, Job CJ Calis, Raph L Hamers, Lillian Katumba Nakatudde, Elizabeth Khauda, Andrew Mukuye, James Ditai, Sibyl P Geelen, Peter Mugyenyi, Tobias F Rinke de Wit, Cissy Kityo
发表日期
2012
期刊
AIDS research and treatment
卷号
2012
期号
1
页码范围
817506
出版商
Hindawi Publishing Corporation
简介
Although the advantages of early infant HIV diagnosis and treatment initiation are well established, children often present late to HIV programs in resource‐limited settings. We aimed to assess factors related to the timing of treatment initiation among HIV‐infected children attending three clinical sites in Uganda. Clinical and demographic determinants associated with early disease (WHO clinical stages 1‐2) or late disease (stages 3‐4) stage at presentation were assessed using multilevel logistic regression. Additionally, semistructured interviews with caregivers and health workers were conducted to qualitatively explore determinants of late disease stage at presentation. Of 306 children initiating first‐line regimens, 72% presented late. Risk factors for late presentation were age below 2 years old (OR 2.83, P = 0.014), living without parents (OR 3.93, P = 0.002), unemployment of the caregiver (OR 4.26, P = 0.001 …
学术搜索中的文章
TS Boender, KCE Sigaloff, J Kayiwa, V Musiime… - AIDS research and treatment, 2012