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Studies on the association between severity of atopic dermatitis (AD) and lifestyle factors in adults have not been conducted in the Netherlands to date.

To explore the association between moderate to severe AD and lifestyle factors in adults in the Dutch general population.

We conducted this cross‐sectional study within the Lifelines Cohort Study by sending a digital AD questionnaire to 135 950 adults in 2020. We extracted data on lifestyle factors from baseline, collected between 2006 and 2013. We analysed the association between lifestyle factors and presence of AD of any severity and of moderate to severe AD, using binary logistic regression and linear regression models.

We enrolled 56 896 participants (mean age 55.8 years, 39.7% males). The lifetime prevalence of self‐reported physician …