作者
Alfonso Eirin, Behzad Ebrahimi, Xin Zhang, Xiang-Yang Zhu, Hui Tang, John A Crane, Amir Lerman, Stephen C Textor, Lilach O Lerman
发表日期
2012/10
期刊
Circulation: Cardiovascular Interventions
卷号
5
期号
5
页码范围
720-728
出版商
Lippincott Williams & Wilkins
简介
Background
The selection of patients with renal artery stenosis (RAS) likely to improve glomerular filtration rate (GFR) after percutaneous transluminal renal angioplasty is difficult. We examined basal hemodynamic and inflammatory factors linked to improved stenotic kidney (STK) function after percutaneous transluminal renal angioplasty in swine RAS.
Methods and Results
Fifteen pigs after 6 weeks of hemodynamically significant RAS were studied before and 4 weeks after technically successful percutaneous transluminal renal angioplasty+stenting. STK and contralateral kidney hemodynamics and function were evaluated by multidetector computed-tomography before and after acetylcholine challenge. Single-kidney deoxyhemoglobin (R2*, reciprocal to blood relaxation) and energy-dependent tubular function were assessed using blood-oxygen-level–dependent magnetic resonance imaging before and after …
引用总数
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