作者
Kenichi Fujii, Stéphane G Carlier, Gary S Mintz, Yi-ming Yang, Issam Moussa, Giora Weisz, George Dangas, Roxana Mehran, Alexandra J Lansky, Edward M Kreps, Michael Collins, Gregg W Stone, Jeffrey W Moses, Martin B Leon
发表日期
2005/4/5
期刊
Journal of the American College of Cardiology
卷号
45
期号
7
页码范围
995-998
出版商
American College of Cardiology Foundation
简介
Objectives
We sought to determine the predictors of stent thrombosis after sirolimus-eluting stent (SES) implantation.
Background
A number of cases of stent thrombosis have been reported after commercial release of the SES in the “real world,” such that the U.S. Food and Drug Administration issued a warning.
Methods
Fifteen patients who developed stent thrombosis after successful SES implantation were analyzed and compared with 45 matched control patients who had no evidence of stent thrombosis.
Results
Minimum stent cross-sectional area (MSA) (4.3 ± 1.6 mm2vs. 6.2 ± 1.9 mm2, p < 0.001) and stent expansion (0.65 ± 0.18 vs. 0.85 ± 0.14, p < 0.001) were significantly smaller in the stent thrombosis group than in the matched control patients. There was no significant difference in the rate of SES malapposition between the groups. However, the presence of a significant residual reference segment stenosis was …
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