作者
KE Boers, SMC Vijgen, Denise Bijlenga, JAM Van Der Post, DJ Bekedam, Anneke Kwee, Paulien CM van der Salm, Maria G van Pampus, MEA Spaanderman, Karin de Boer, Johannes J Duvekot, HA Bremer, THM Hasaart, FMC Delemarre, Kitty WM Bloemenkamp, Claudia A van Meir, Christine Willekes, EJ Wijnen, Monique Rijken, Saskia le Cessie, Frans JME Roumen, Jim G Thornton, Jan MM van Lith, Ben WJ Mol, Sicco A Scherjon
发表日期
2010/12/21
期刊
Bmj
卷号
341
出版商
British Medical Journal Publishing Group
简介
Objective To compare the effect of induction of labour with a policy of expectant monitoring for intrauterine growth restriction near term.
Design Multicentre randomised equivalence trial (the Disproportionate Intrauterine Growth Intervention Trial At Term (DIGITAT)).
Setting Eight academic and 44 non-academic hospitals in the Netherlands between November 2004 and November 2008.
Participants Pregnant women who had a singleton pregnancy beyond 36+0 weeks’ gestation with suspected intrauterine growth restriction.
Interventions Induction of labour or expectant monitoring.
Main outcome measures The primary outcome was a composite measure of adverse neonatal outcome, defined as death before hospital discharge, five minute Apgar score of less than 7, umbilical artery pH of less than 7.05, or admission to the intensive care unit. Operative delivery (vaginal instrumental delivery or caesarean section) was a …
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