作者
Christian E Althoff, Joachim Sieper, In-Ho Song, Hildrun Haibel, Anja Weiß, Torsten Diekhoff, Martin Rudwaleit, Bruce Freundlich, Bernd Hamm, Kay-Geert A Hermann
发表日期
2013/6/1
期刊
Annals of the rheumatic diseases
卷号
72
期号
6
页码范围
967-973
出版商
BMJ Publishing Group Ltd
简介
Objective
To evaluate active inflammatory lesions (AIL) and structural changes (SC) in patients with active non-radiographic axial spondyloarthritis (nr-axSpA) compared with patients with ankylosing spondylitis (AS) on whole-body MRI (wb-MRI).
Method
75 patients with active disease and a symptom duration of <5 years (39 with AS and 36 with nr-axSpA) were investigated with a comprehensive wb-MRI protocol and scored for AIL and SC in the spine, sacroiliac joints (SIJs) and non-axial manifestations.
Results
92% of patients with AS showed active inflammation in the SIJ, 53% in the spine and 94% and 39%, respectively, in the nr-axSpA group. There was a non-significant trend towards more inflammation in patients with AS compared with patients with nr-axSpA in SIJs and spine. Peripheral enthesitis/osteitis was more common in patients with AS (n=22) than in those with nr-axSpA (n=12) (p=0.05). SC were …
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CE Althoff, J Sieper, IH Song, H Haibel, A Weiß… - Annals of the rheumatic diseases, 2013