作者
Maja Matanović Škugor, Vlado Štimac, Ivana Palej, Đurdjica Lugarić, Hana Čipčić Paljetak, Darko Filić, Marina Modrić, Ivica Đilović, Dubravka Gembarovski, Stjepan Mutak, Vesna Eraković Haber, David J Holmes, Zrinka Ivezić-Schoenfeld, Sulejman Alihodžić
发表日期
2010/9/1
期刊
Bioorganic & medicinal chemistry
卷号
18
期号
17
页码范围
6547-6558
出版商
Pergamon
简介
The synthesis and antimicrobial activity of a new class of macrolide antibiotics which consist of a macrolide scaffold and a quinolone unit covalently connected by an appropriate linker are described. Optimization of several synthetic steps and structural properties of lead compound 26 are discussed. Promising antibacterial properties of this compound and some of its analogues are reported.
学术搜索中的文章
MM Škugor, V Štimac, I Palej, Đ Lugarić, HČ Paljetak… - Bioorganic & medicinal chemistry, 2010