作者
Marco Vincenzo Lenti, Luca Pasina, Sara Cococcia, Laura Cortesi, Emanuela Miceli, Costanza Caccia Dominioni, Martina Pisati, Caterina Mengoli, Francesco Perticone, Alessandro Nobili, Antonio Di Sabatino, Gino Roberto Corazza, REPOSI Investigators
发表日期
2019/3/1
期刊
European Journal of Internal Medicine
卷号
61
页码范围
54-61
出版商
Elsevier
简介
Background
Gastrointestinal bleeding (GIB) is burdened by high mortality rate that increases with aging. Elderly patients may be exposed to multiple risk factors for GIB. We aimed at defining the impact of GIB in elderly patients.
Methods
Since 2008, samples of elderly patients (age ≥ 65 years) with multimorbidity admitted to 101 internal medicine wards across Italy have been prospectively enrolled and followed-up (REPOSI registry). Diagnoses of GIB, length of stay (LOS), mortality rate, and possible risk factors, including drugs, index of comorbidity (Cumulative Illness Rating Scale [CIRS]), polypharmacy, and chronic diseases were assessed. Adjusted multivariate logistic regression models were computed.
Results
3872 patients were included (mean age 79 ± 7.5 years, F:M ratio 1.1:1). GIB was reported in 120 patients (mean age 79.6 ± 7.3 years, F:M 0.9:1), with a crude prevalence of 3.1%. Upper GIB …
学术搜索中的文章
MV Lenti, L Pasina, S Cococcia, L Cortesi, E Miceli… - European Journal of Internal Medicine, 2019