作者
Luca Pasina, Codjo D Djade, Alessandro Nobili, Mauro Tettamanti, Carlotta Franchi, Francesco Salerno, Salvatore Corrao, Alessandra Marengoni, Alfonso Iorio, Maura Marcucci, PierMannuccio Mannucci
发表日期
2013/10
期刊
pharmacoepidemiology and drug safety
卷号
22
期号
10
页码范围
1054-1060
简介
Purpose
The aim of this study is to assess the prevalence of patients exposed to potentially severe drug–drug interactions (DDIs) at hospital admission and discharge and the related risk of in‐hospital mortality and adverse clinical events, readmission, and all‐cause mortality at 3 months.
Methods
This cross‐sectional, prospective study was held in 70 Italian internal medicine and geriatric wards. Potentially severe DDIs at hospital admission and discharge; risk of in‐hospital mortality and of adverse clinical events, readmission, and all‐cause mortality at 3‐month follow‐up.
Results
Among 2712 patients aged 65 years or older recruited at hospital admission, 1642 (60.5%) were exposed to at least one potential DDI and 512 (18.9%) to at least one potentially severe DDI. Among 2314 patients discharged, 1598 (69.1%) were exposed to at least one potential DDI and 1561 (24.2%) to at least one potentially severe …
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L Pasina, CD Djade, A Nobili, M Tettamanti, C Franchi… - pharmacoepidemiology and drug safety, 2013